Clinical feasibility of high-resolution single-shot diffusion tensor trace -weighted (ssTW) MRI

and negative (red) bipolar gradients results in cancelling contributions from off-diagonal diffusion tensor elements to the DW signal. Figure 2: A. Trace weighted MRIs acquired using our ssTW method in 15s across the entire brain. B. Brain tissue regions-of-interest (ROIs) C. Mean ADC map calculated from the ssTW scan. D. Mean ADC map calculated using DTI with 20 directions in 2 min. E. Direction-encoded color (DEC) fractional anisotropy map derived from the DTI scan. Clinical feasibility of high-resolution single-shot diffusion tensor trace -weighted (ssTW) MRI Alexandru V Avram, Joelle E Sarlls, Raisa Z Freidlin, and Peter J Basser Section on Tissue Biophysics and Biomimetics, NICHD, National Institutes of Health, Bethesda, MD, United States, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States, Division of Computational Bioscience, CIT, National Institutes of Health, Bethesda, Maryland, United States